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Kinetics and mechanism of monomolecular heterolysis of framework compounds. VI. Dehydrobromination of 2-bromo-2-methyladamantane in acetonitrile

Journal Article · · J. Org. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:5887587

The kinetics of dehydrobromination of 2-bromo-2-methyladamantane in acetonitrile were studied in the presence of triphenylverdazyl as internal indicator; k/sub 25/ = 8.57 /times/ 10/sup /minus/5/ sec/sup /minus/1/, /Delta/H/sup /ne// 79 kJ/mole, /Delta/S/sup /ne// /minus/58 kJ/mole /times/ deg. Additions of water, phenols, lithium perchlorate, and bromides increase the reaction rate, and additions of nitrates and picrates reduce it. A similar pattern is observed in the dehydrobromination of tert-butyl bromide in acetonitrile. In the presence of tetraethylammonium chloride the heterolysis rate of 2-bromo-2-methyladamantane decreases, while that of tert-butyl bromide increases. The positive salt effect is explained by stabilization of the transition state by the salt, and the negative salt effect is explained by the reaction of the anion with the sterically separated or solvent-separated ion pair of the substrate.

Research Organization:
Kiev Polytechnical Institute (USSR)
OSTI ID:
5887587
Journal Information:
J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 24:3; ISSN JOCYA
Country of Publication:
United States
Language:
English

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