Distribution of inhaled /sup 238/PuO/sub 2/ particles in Syrian hamster lungs

Journal Article · Sun Nov 01 04:00:00 EST 1981 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575662· OSTI ID:5887269

Diel, J H; Mewhinney, J A; B, Snipes M

Syrian hamsters were exposed by inhalation to a monodisperse aerosol of /sup 238/PuO/sub 2/, and the distribution of particles in their lungs was studied as a function of time after exposure. The particles deposited preferentially in the central regions of the lung, moved toward the periphery, and were cleared from all regions, except regions receiving high levels of damage, with about equal efficiency. The local distribution of particles in lung was less uniform with increasing time and lung burden of plutonium.

• Research Organization: Lovelace Biomedical and Environmental Research Inst., Albuquerque, NM
• DOE Contract Number: AC04-76EV01013
• OSTI ID: 5887269
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 88:2; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE COMPOUNDS
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CHALCOGENIDES
DISTRIBUTION
EVEN-EVEN NUCLEI
HAMSTERS
HEAVY NUCLEI
INHALATION
INJURIES
INTAKE
ISOTOPES
LUNGS
MAMMALS
NUCLEI
ORGANS
OXIDES
OXYGEN COMPOUNDS
PLUTONIUM 238
PLUTONIUM COMPOUNDS
PLUTONIUM ISOTOPES
PLUTONIUM OXID
PLUTONIUM OXIDE
PLUTONIUM OXIDES
RADIATION EFFECTS
RADIATION INJURIES
RADIOISOTOPES
RESPIRATORY SYSTEM
RODENTS
TIME DEPENDENCE
TISSUE DISTRIBUTION
TOXICITY
TRANSURANIUM COMPOUNDS
VERTEBRATES
YEARS LIVING RADIOISOTOPES