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Enhancement of mass resolution in the quadrupole ion trap via resonance ejection

Conference ·
OSTI ID:5882754

The Finnigan MAT ion trap mass spectrometer (ITMS) has unit mass resolution and a nominal upper mass/charge limit of only 650 when operated in the standard mass-selective instability method for acquiring mass spectra. Mass resolution up to {approx}2500 can be achieved with the use of the axial modulation technique. Ions can also be ejected at a q{sup z} value other than that corresponding to the mass-selective instability boundary by application of an auxiliary signal to the end-cap electrodes. When the frequency of this signal is resonant with the secular frequency for a particular m/z, such ions can become kinetically excited and ejected from the trap via a process known as resonance ejection. We demonstrate the capability to mass-selectively isolate or eject ions over a wide mass range and to generate mass spectra of electrospray-generated ions by scanning the frequency of the resonance ejection signal applied to the end-cap electrodes. A block diagram of the experimental modifications to the ITMS required for frequency-swept resonance ejection is shown. 2 refs., 5 figs.

Research Organization:
Oak Ridge National Lab., TN (USA)
Sponsoring Organization:
DOE; USDOE, Washington, DC (USA)
DOE Contract Number:
AC05-84OR21400
OSTI ID:
5882754
Report Number(s):
CONF-9105181-3; ON: DE91012507
Country of Publication:
United States
Language:
English