/ital In/ /ital vivo/ measurement of cortical bone lead using polarized x rays

Journal Article · Sat Jul 01 00:00:00 EDT 1989 · Med. Phys.; (United States)

OSTI ID:5877148

Wielopolski, L; Rosen, J F; Slatkin, D N; Zhang, R; Kalef-Ezra, J A

An x-ray fluorescence system which utilizes polarized radiation to measure lead in vivo in human subjects is described. The minimum detection limit is approximately 6.4 ppm wet weight lead in the cortex of the tibia with 4 mm of overlying soft tissue. This appears to be adequate for assessing lead stores in lead-toxic preschool children. The measurement requires 16.5 min and is associated with an effective equivalent whole body dose to the subject of 2.5 /mu/Sv. The system, its calibration and its validation are described herein.

• Research Organization: Radiation Oncology Department, University Hospital at Stony Brook, State University of New York, Stony Brook, New York 11794-7028(US); Department of Pediatrics, Albert Einstein College of Medicine of Yeshiva University, Montefiore Medical Center, Bronx, New York 10467-2490; Medical Department, Brookhaven National Laboratory, Upton, New York 11973; Biology Department, Tsinghua University, Beijing, People's Republic of China
• OSTI ID: 5877148
• Journal Information: Med. Phys.; (United States), Vol. 16:4
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BONE TISSUES
BIOMEDICAL RADIOGRAPHY
CHILDREN
SCREENING
LEAD
TOXICITY
FLUORESCENCE
IN VIVO
X-RAY RADIOGRAPHY
AGE GROUPS
ANIMAL TISSUES
BODY
CONNECTIVE TISSUE
DIAGNOSTIC TECHNIQUES
ELEMENTS
INDUSTRIAL RADIOGRAPHY
LUMINESCENCE
MEDICINE
METALS
NUCLEAR MEDICINE
RADIOLOGY
TISSUES
560300* - Chemicals Metabolism & Toxicology