DOE/CEC (Department of Energy/Commission of the European Communities) workshop on critical evaluation of radiobiological data to biophysical modeling
The Department of Energy's Office of Health and Environmental Research and the Commission of the European Communities (CEC) Radiation Protection Program support the majority of Research in the Field of Radiobiological Modeling. This field of science develops models based on scientifically sound principles to predict biological response (at the cellular, molecular, and animal level) to exposure to low level ionizing radiation. Biophysical models are an important tool for estimating response of ionizing radiation at low doses and dose rates. Generally speaking, the biophysical models can be classified into two groups: (1) mechanistic models and (2) phenomenological models. Mechanistic models are based on some assumptions about the physical, chemical, or biological mechanisms of action in association with radiobiological data whereas the phenomenological models are based solely on available experimental data on radiobiological effects with less emphasis on mechanisms of action. There are a number of these models which are being developed. Since model builders rely on radiobiological data available in the literature either to develop mechanistic or phenomenological models, it is essential that a critical evaluation of existing radiobiological data be made and data that is generally considered good and most appropriate for biophysical modeling be identified. A Workshop jointly sponsored by the DOE and the CEC was held at Oak Ridge, Tennessee from June 23--25, 1988, to review the data available from physical and chemical, cellular and molecular and animal studies with ionizing radiation.
- Research Organization:
- USDOE Office of Energy Research, Washington, DC (USA). Office of Health and Environmental Research; Commission of the European Communities, Brussels (Belgium)
- OSTI ID:
- 5857633
- Report Number(s):
- CONF-8806237-; ON: DE89015214
- Resource Relation:
- Conference: DOE/CEC workshop, Oak Ridge, TN, USA, 22-24 Jun 1988; Other Information: Portions of this document are illegible in microfiche products
- Country of Publication:
- United States
- Language:
- English
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