A biokinetic model for {sup 137}Cs

Journal Article · Fri Aug 01 04:00:00 EDT 1997 · Health Physics

DOI:https://doi.org/10.1097/00004032-199708000-00004· OSTI ID:585242

Melo, D R; Lipsztein, J L; Oliveira, C A.N. ^[1]; Lundgren, D L ^[2]

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1. Instituto de Radioprotecao e Dosimetria, Rio de Janeiro (Brazil)
2. Inhalation Toxicology Research Institute, Albuquerque, NM (United States); and others

An improved biokinetic model for {sup 137}Cs in humans was developed based on an analysis of data obtained from individuals internally contaminated during an accident in Goiania, Brazil, and other data. Seventeen children (ten girls and seven boys 1-10 y old), ten adolescents (four females and six males), and thirty adults, (fifteen females and fifteen males) contaminated in the accident in Goiania contributed to this study. {sup 137}Cs retention was determined through periodic measurements in a whole-body counter. In addition to the data on {sup 137}Cs retention from these individuals, data from a study on the metabolism of {sup 137}Cs in immature, adult, and aged Beagle dogs and data from the literature were used in the formulation of the {sup 137}Cs biokinetic model presented. Mathematically, the retention of cesium is described by three exponential terms, and the retention model is based on a step function of body weight. When the ICRP Publication 56 model for cesium was compared to the model suggested in this paper, it was determined that the ICRP model predicts lower effective doses in 5-y-old children and higher effective doses in infants, adolescents, and adults.

• Sponsoring Organization: USDOE
• DOE Contract Number: AC04-76EV01013
• OSTI ID: 585242
• Journal Information: Health Physics, Journal Name: Health Physics Journal Issue: 2 Vol. 73; ISSN HLTPAO; ISSN 0017-9078
• Country of Publication: United States
• Language: English

Related Subjects

56 BIOLOGY AND MEDICINE
APPLIED STUDIES
ADOLESCENTS
AGE DEPENDENCE
BRAZIL
CESIUM 137
DOGS
METABOLISM
RADIATION DOSES
RETENTION
WEIGHT