Complete proton and carbon-13 NMR assignment of the alkaloid geopyrotoxin through the use of homonuclear Hartmann-Hahn and two-dimensional NMR spectroscopy
Journal Article
·
· J. Am. Chem. Soc.; (United States)
Three different types of modern NMR techniques have been used to obtain a complete proton and carbon-13 assignment of the alkaloid geopyrotoxin. In addition to the two-dimensional phase-sensitive homo- and heteronuclear shift correlation methods, use of the recently proposed one-dimensional homonuclear Hartmann-Hahn difference experiment was crucial for obtaining the required long-range connectivity. Guidelines are presented for optimal use of these techniques. Experiments were performed at 500-MHz /sup 1/H frequency, using 8 mg of sample. 53 references, 7 figures, 1 table.
- Research Organization:
- National Institutes of Health, Bethesda, MD
- OSTI ID:
- 5849146
- Journal Information:
- J. Am. Chem. Soc.; (United States), Journal Name: J. Am. Chem. Soc.; (United States) Vol. 108:5; ISSN JACSA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400302* -- Organic Chemistry-- Isotope Effects-- (-1987)
ALKALOIDS
CARBON 13
CARBON ISOTOPES
DATA
ELEMENTS
EVEN-ODD NUCLEI
EXPERIMENTAL DATA
FREQUENCY RANGE
HYDROGEN
INFORMATION
ISOTOPES
LIGHT NUCLEI
MAGNETIC RESONANCE
MHZ RANGE
MHZ RANGE 100-1000
NONMETALS
NUCLEAR MAGNETIC RESONANCE
NUCLEI
NUMERICAL DATA
ORGANIC COMPOUNDS
RESONANCE
STABLE ISOTOPES
STRUCTURAL CHEMICAL ANALYSIS
TWO-DIMENSIONAL CALCULATIONS
400302* -- Organic Chemistry-- Isotope Effects-- (-1987)
ALKALOIDS
CARBON 13
CARBON ISOTOPES
DATA
ELEMENTS
EVEN-ODD NUCLEI
EXPERIMENTAL DATA
FREQUENCY RANGE
HYDROGEN
INFORMATION
ISOTOPES
LIGHT NUCLEI
MAGNETIC RESONANCE
MHZ RANGE
MHZ RANGE 100-1000
NONMETALS
NUCLEAR MAGNETIC RESONANCE
NUCLEI
NUMERICAL DATA
ORGANIC COMPOUNDS
RESONANCE
STABLE ISOTOPES
STRUCTURAL CHEMICAL ANALYSIS
TWO-DIMENSIONAL CALCULATIONS