Production of reactive oxygen species by polyhalogenated cyclic hydrocarbons (PCH). Final report, 15 June 1990-14 June 1993

Technical Report · Mon Jun 14 00:00:00 EDT 1993

OSTI ID:5845135

Stohs, S J

During the past three years, excellent progress has been made relative to the specific objectives of this project. The results strongly support the hypothesis that the ability of polyhalogenated cyclic hydrocarbons (PCH) to induce production of reactive oxygen species may contribute to many of the toxic manifestations associated with these xenobiotics. As a consequence of the studies, seven papers have been presented at national and international meetings. In addition, twelve manuscripts have been published, three manuscripts are in press, and one manuscript has been submitted. Furthermore, several manuscripts are in the process of being written. Copies of the reprints and manuscripts are appended.

• Research Organization: Creighton Univ., Omaha, NE (United States). Health Sciences Center
• OSTI ID: 5845135
• Report Number(s): AD-A-269354/7/XAB; CNN: AFOSR-90-0278
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
HALOGENATED AROMATIC HYDROCARBONS
CHEMICAL REACTIONS
XENOBIOTICS
TOXICITY
DIOXIN
HYPOTHESIS
OXYGEN
AROMATICS
ELEMENTS
HETEROCYCLIC COMPOUNDS
NONMETALS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
400201* - Chemical & Physicochemical Properties
560300 - Chemicals Metabolism & Toxicology