Dose dependence of complication rates in cervix cancer radiotherapy
Journal Article
·
· Int. J. Radiat. Oncol., Biol. Phys.; (United States)
The population selected for this study was a group of 410 Stage IIB and III squamous cell Ca cervix patients treated at the Radiumhemmet between the years 1958-1966. A total of 48 of these patients developed moderate-to-severe rectal and/or bladder complications. Of these, 33 were evaluable with respect to dose-dependence of complications, that is, complete intracavitary dose measurements and external beam dose calculations, no chemotherapy or electrocautery, and complete clinical radiotherapy records. A group of 57 randomly selected uninjured patients were used as controls. Results show good correlation between dose, expressed in TDF units, and complication rates for both rectal and bladder injuries. Severity of rectal injury was observed to increase with increase in dose, although no such correlation was observed for bladder injuries. Mean delays in the expression of symptoms of injury were 10 months for the rectum and 22 months for the bladder.
- Research Organization:
- Harper-Grace Hospitals, Detroit, MI
- OSTI ID:
- 5843241
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 1; ISSN IOBPD
- Country of Publication:
- United States
- Language:
- English
Similar Records
Bladder and rectal complications following radiotherapy for cervix cancer
Correlations of dose and time-dose-fractionation factors (TDF) with treatment results and side effects in cancer of the uterine cervix
High-dose rate intracavitary therapy for carcinoma of the uterine cervix. II. Risk factors for rectal complication
Journal Article
·
Thu Dec 31 23:00:00 EST 1987
· Gynecol. Oncol.; (United States)
·
OSTI ID:5297438
Correlations of dose and time-dose-fractionation factors (TDF) with treatment results and side effects in cancer of the uterine cervix
Journal Article
·
Fri Feb 28 23:00:00 EST 1986
· Gynecol. Oncol.; (United States)
·
OSTI ID:5738374
High-dose rate intracavitary therapy for carcinoma of the uterine cervix. II. Risk factors for rectal complication
Journal Article
·
Sun Jan 31 23:00:00 EST 1988
· Int. J. Radiat. Oncol., Biol. Phys.; (United States)
·
OSTI ID:5352450
Related Subjects
550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
BODY
CARCINOMAS
DELAYED RADIATION EFFECTS
DIGESTIVE SYSTEM
DISEASES
FEMALE GENITALS
FEMALES
GASTROINTESTINAL TRACT
INTESTINES
LARGE INTESTINE
MAMMALS
MAN
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PRIMATES
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
RECTUM
SIDE EFFECTS
THERAPY
URINARY TRACT
VERTEBRATES
WOMEN
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
BODY
CARCINOMAS
DELAYED RADIATION EFFECTS
DIGESTIVE SYSTEM
DISEASES
FEMALE GENITALS
FEMALES
GASTROINTESTINAL TRACT
INTESTINES
LARGE INTESTINE
MAMMALS
MAN
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PRIMATES
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
RECTUM
SIDE EFFECTS
THERAPY
URINARY TRACT
VERTEBRATES
WOMEN