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Aerial oxidation of hydrazines to nitrosamines

Journal Article · · Environmental and Molecular Mutagenesis; (USA)
; ;  [1]
  1. NCI-Frederick Cancer Research and Development Center, MD (USA)
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When 1,1-dimethylhydrazine and N-aminopiperidine were deliberately exposed to air substantial amounts of the corresponding carcinogenic nitrosamines were formed. Unoxidized samples of 1,1-dimethylhydrazine were not mutagenic while oxidized samples (which contained much higher levels of nitrosamines) were mutagenic. Both unoxidized and oxidized samples of N-aminopiperidine were mutagenic.
OSTI ID:
5840037
Journal Information:
Environmental and Molecular Mutagenesis; (USA), Journal Name: Environmental and Molecular Mutagenesis; (USA) Vol. 17:1; ISSN EMMUE; ISSN 0893-6692
Country of Publication:
United States
Language:
English

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Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
BACTERIA
CHEMICAL REACTIONS
CHROMATOGRAPHY
GAS CHROMATOGRAPHY
HYDRAZINE
MICROORGANISMS
MUTAGEN SCREENING
MUTANTS
NITROGEN COMPOUNDS
NITROSAMINES
NITROSO COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OXIDATION
REVERTANTS
SALMONELLA
SALMONELLA TYPHIMURIUM
SCREENING
SEPARATION PROCESSES