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Myocardial uptake of technetium-99m stannous pyrophosphate in experimental viral myopericarditis. [Mice]

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:5829684
; ; ;

Distribution of technetium-99m stannous pyrophosphate was studied in mice with experimentally induced viral myopericarditis. Myocardial and bone uptakes of Tc-PPi were compared in 55 mice inoculated with coxsackievirus B3 (Nancy strain). The myocardium-to-bone uptake ratio in 33 mice with myopericarditis was increased to a greater extent than that seen in 22 mice without myopericarditis (p < 0.001). In the severely involved heart, the uptake per gram exceeded that in the bone. Myocardial uptake in myopericarditis can be visualized on a whole-body image using a pinhole collimator and a left lateral view. Our experimental studies suggest the potential clinical usefulness of myocardial scintigraphy in viral myopericarditis.

Research Organization:
Kyoto Univ., Japan
OSTI ID:
5829684
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 20:10; ISSN JNMEA
Country of Publication:
United States
Language:
English

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Related Subjects

550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
560172* -- Radiation Effects-- Nuclide Kinetics &amp; Toxicology-- Animals-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPLEXES
COUNTING TECHNIQUES
DATA
DATA FORMS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DISTRIBUTION
EXPERIMENTAL DATA
HEART
HOURS LIVING RADIOISOTOPES
INFECTIOUS DISEASES
INFLAMMATION
INFORMATION
INTERMEDIATE MASS NUCLEI
ISOLATED VALUES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MEMBRANES
MICE
MICROORGANISMS
MUSCLES
MYOCARDIUM
NUCLEI
NUMERICAL DATA
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PARASITES
PATHOLOGICAL CHANGES
PERICARDIUM
PHOSPHORUS COMPOUNDS
PYROPHOSPHATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RODENTS
SCINTISCANNING
SEROUS MEMBRANES
SKELETON
TECHNETIUM 99
TECHNETIUM ISOTOPES
TIN COMPLEXES
TISSUE DISTRIBUTION
VERTEBRATES
VIRUSES
YEARS LIVING RADIOISOTOPES