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/sup 203/Hg excretion and tissue distribution in Holstein calves following single tracer intravenous doses of methyl mercury chloride or mercuric chloride

Journal Article · · J. Anim. Sci.; (United States)
OSTI ID:5824932
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Eight male Holstein calves were given a single tracer intravenous dose of /sup 203/Hg as mercuric chloride or methyl mercury chloride 7 days before sacrifice. Total 7-day fecal and urinary Hg excretions were much higher from mercuric chloride dosing than from methyl mercury chloride. Retention of Hg from mercuric chloride was greater in kidney, liver, spleen, lung, testicle, rib shaft, tibia joint, tibia shaft, abomasum, small intestine, cecum, large intestine and pancreas and less in brain cerebellum and cerebrum, supraspinatus muscle and heart, and substantially lower in psoas and semitendinosus muscles. Fifteen minutes after dosing, whole blood Hg was lower from mercuric chloride followed by a similar rapid clearance for both Hg forms. Throughout the 7-day period, plasma Hg was greater from mercuric chloride. In red blood cells, Hg from methyl mercury chloride was higher during the first 2 hr after dosing, with no significant differences thereafter. 5 references, 2 figures, 1 table.

Research Organization:
Univ. of Georgia, Athens
OSTI ID:
5824932
Journal Information:
J. Anim. Sci.; (United States), Journal Name: J. Anim. Sci.; (United States) Vol. 40:4; ISSN JANSA
Country of Publication:
United States
Language:
English

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Related Subjects

553001 -- Agriculture & Food Technology-- Tracer Techniques-- (-1987)
560303* -- Chemicals Metabolism & Toxicology-- Plants-- (-1987)
60 APPLIED LIFE SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL ACCUMULATION
BLOOD-PLASMA CLEARANCE
CALVES
CATTLE
CHLORIDES
CHLORINE COMPOUNDS
CLEARANCE
COMPARATIVE EVALUATIONS
DAYS LIVING RADIOISOTOPES
DISTRIBUTION
DOMESTIC ANIMALS
EVEN-ODD NUCLEI
EXCRETION
HALIDES
HALOGEN COMPOUNDS
HEAVY NUCLEI
ISOTOPES
MAMMALS
MERCURY 203
MERCURY CHLORIDES
MERCURY COMPOUNDS
MERCURY HALIDES
MERCURY ISOTOPES
METABOLISM
METHYLMERCURY
NUCLEI
ORGANIC COMPOUNDS
ORGANIC MERCURY COMPOUNDS
RADIOISOTOPES
RADIONUCLIDE KINETICS
RETENTION
RUMINANTS
TISSUE DISTRIBUTION
VERTEBRATES