Increased susceptibility to radiofrequency radiation due to pharmacological agents

Journal Article · Thu Nov 01 04:00:00 EST 1984 · Aviat., Space Environ. Med.; (United States)

OSTI ID:5820584

Jauchem, J R; Frei, M R; Heinmets, F

The effects of chlorpromazine, methysergide, and propranolol on thermal responses to 2.8 GHz radiofrequency radiation were examined in anesthetized rats. During intermittent exposure at an average power density of 60 mW/sq cm (specific absorption rate, 14 W/kg), when colonic temperature was not allowed to rise above 39.5 C, none of the pharmacological agents had any significant effects on thermal responses. When exposure was continued until lethal temperatures resulted, animals which were administered chlorpromazine, methysergide, or propranolol exhibited significantly shorter survival times than saline-treated animals. Propranolol administration caused the greatest decrease in survival time and resulted in a significantly lower lethal temperature than that which occurred in saline-treated animals. 29 references.

• Research Organization: Trinity Univ., San Antonio, TX
• OSTI ID: 5820584
• Journal Information: Aviat., Space Environ. Med.; (United States), Journal Name: Aviat., Space Environ. Med.; (United States) Vol. 55; ISSN ASEMC
• Country of Publication: United States
• Language: English

Related Subjects

560400* -- Other Environmental Pollutant Effects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
ANIMALS
AZINES
BIOLOGICAL EFFECTS
BIOLOGY
BODY TEMPERATURE
CENTRAL NERVOUS SYSTEM AGENTS
CENTRAL NERVOUS SYSTEM DEPRESSANTS
CHLORPROMAZINE
DRUGS
ELECTROMAGNETIC RADIATION
HETEROCYCLIC COMPOUNDS
HYPNOTICS AND SEDATIVES
MAMMALS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PHARMACOLOGY
PHENOTHIAZINES
PSYCHOTROPIC DRUGS
RADIATIONS
RADIOBIOLOGY
RADIOWAVE RADIATION
RATS
REAGENTS
RODENTS
SENSITIZERS
TRANQUILIZERS
VERTEBRATES