Quantitative autoradiography with radiopharmaceuticals, Part 1: Digital film-analysis system by videodensitometry: concise communication
Journal Article
·
· J. Nucl. Med.; (United States)
OSTI ID:5820468
A simple low-cost digital film-analysis system using videodensitometry was developed to quantitate autoradiograms. It is based on a TV-film analysis system coupled to a minicomputer. Digital sampling of transmitted light intensities through the autoradiogram is performed with 8-bit gray levels according to the selected array size (128 X 128 to 1024 X 1024). The performance characteristics of the system provide sufficient stability, uniformity, linearity, and intensity response for use in quantitative analysis. Digital images of the autoradiograms are converted to radioactivity content, pixel by pixel, using step-wedge standards. This type of low-cost system can be installed on conventional mini-computers commonly used in modern nuclear medical facilities. Quantitative digital autoradiography can play an important role, with applications stretching from dosimetry calculations of radiopharmaceuticals to metabolic studies in conjunction with positron-emission tomography.
- Research Organization:
- Brookhaven National Laboratory, Upton, New York
- OSTI ID:
- 5820468
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 24:3; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Quantitative autoradiography with radiopharmaceuticals, Part 2: Applications in radiopharmaceutical research: concise communication
Microcomputer-based digital image analysis system for quantitative autoradiography
Development of a quantitative autoradiography image analysis system
Journal Article
·
Mon Feb 28 23:00:00 EST 1983
· J. Nucl. Med.; (United States)
·
OSTI ID:5821772
Microcomputer-based digital image analysis system for quantitative autoradiography
Journal Article
·
Thu Dec 31 23:00:00 EST 1987
· Am. J. Physiol. Imag.; (United States)
·
OSTI ID:6770400
Development of a quantitative autoradiography image analysis system
Conference
·
Fri Feb 28 23:00:00 EST 1986
· Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)
·
OSTI ID:5429648