Process for labeling single-stranded nucleic acids and hybridization probes
Patent
·
OSTI ID:5815287
A process is described for labeling a single-stranded nucleic acid which comprises the steps of: contacting the nucleic acid with one or more labeling compositions containing an alkylating moiety, a divalent organic moiety, and a monovalent label moiety; and activating the complex so as to induce the alkylating moiety to bond covalently to the nucleic acid.
- Assignee:
- Cetus Corp., Emeryville, CA
- Patent Number(s):
- US 4822731
- OSTI ID:
- 5815287
- Resource Relation:
- Patent File Date: Filed date 9 Jan 1986
- Country of Publication:
- United States
- Language:
- English
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