Syntheses with stable isotopes of carbon, nitrogen, and oxygen
Methods, techniques, ideas, information, and references to prepare compounds labeled with stable isotopes of carbon, nitrogen, and oxygen are presented, which can be used in selecting or devising synthetic schemes. By studying and comparing methods that other investigators have applied to problems in isotopic labeling, the task of deciding on suitable syntheses for incorporating isotopes into various other compounds can be considerably simplified. The major portion of the book is devoted to synthetic procedures that have been used for preparation of specific labeled compounds. The descriptions are often given in sufficient detail that they can be applied or modified without necessity for recourse to the original literature. Methods can be compared, feasibility for extensions to other isotope isomers or to related compounds can be assessed, and requirements for apparatus, materials, time, effort, and skills can be evaluated. Additional methods and speculations are presented for a number of other compounds whose syntheses are not given in detail. A few biosynthetic preparations, which afford specific products in good isotopic yield, are described; certain other applications of biological methods are considered briefly. Arrangement of the procedures into chapters according to functional groups is somewhat arbitrary; that is, not all preparations of carboxylic acids will be found in the chapter dealing with acids and derivatives; certain alcohols appear as components in multistep syntheses in the chapter on hydrocarbons; some compounds could just as well have been placed elsewhere; and so on. Thus it is important to use the index. Following the introductory chapter, the contents of this book are as follows: (1) acids, anhydrides, amids, esters, and nitriles; (2) aldehydes and ketones; (3) alcohols, ethers, and phenols; (4) amines, and hydrocarbons; (5) heterocyclic compounds; and (6) other compounds.
- OSTI ID:
- 5808449
- Country of Publication:
- United States
- Language:
- English
Similar Records
Organic and petroleum chemistry for nonchemists
SYNTHESES OF SOME NEW MONO-ACID ESTERS
Related Subjects
400301* -- Organic Chemistry-- Chemical & Physicochemical Properties-- (-1987)
ALCOHOLS
ALDEHYDES
AMIDES
AMINES
ANHYDRIDES
CARBON 13
CARBON ISOTOPES
ESTERS
ETHERS
EVEN-EVEN NUCLEI
EVEN-ODD NUCLEI
HETEROCYCLIC COMPOUNDS
HYDROCARBONS
HYDROXY COMPOUNDS
ISOTOPES
KETONES
LABELLED COMPOUNDS
LABELLING
LIGHT NUCLEI
NITRILES
NITROGEN 15
NITROGEN ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
OXYGEN 18
OXYGEN ISOTOPES
STABLE ISOTOPES
SYNTHESIS