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Mutagenicity and chemical analysis of airborne particulates from a rural area in Italy

Journal Article · · Environ. Manage.; (United States)
Mutagenic activities of a sample of characterized airborne particulates collected in a rural location near Ispra (Italy) during the summer of 1980 were detected by the Ames test using TA 1537, TA 1538, TA 98, and TA 100 Salmonella strains. Eight chemical classes fractionated from the CH/sub 2/Cl/sub 2/ extract of the particulates were bioassayed. Periodical samples were taken in the same location from March to December 1981, extracted in dimethyl sulfoxide (DMSO), and directly tested with TA 1537, TA 98, and TA 100 Salmonella strains. For all the strains the mutagenicity varied markedly according to the season, the cold-month samples being much more mutagenic than the summer-month samples. The addition of S9 increased the mutagenicity (twofold) of the cold-month samples. The higher mutagenicity of the samples collected during the cold months could be due to greater amounts of mutagens produced by the combustion processes of domestic heating.
Research Organization:
Universita di Pisa, Ispra, Italy
OSTI ID:
5780170
Journal Information:
Environ. Manage.; (United States), Journal Name: Environ. Manage.; (United States) Vol. 6:6; ISSN EMNGD
Country of Publication:
United States
Language:
English