Quantitative comparisons of acute toxicity of organic chemicals to rat and fish

Journal Article · Fri Nov 30 23:00:00 EST 1984 · Ecotoxicol. Environ. Saf.; (United States)

DOI:https://doi.org/10.1016/0147-6513(84)90013-7· OSTI ID:5776296

Janardan, S K; Olson, C S; Schaeffer, D J

Relationships between the acute toxicity of chemicals to fish (LC50) and rat (LD50) were analyzed using a Model II regression analysis after logarithmic transformation. (Model II regression assumes errors in both variables.) Significant correlations were found among bluegill and fathead minnow LC50S and rat LD50 values for the priority pollutants. Fathead minnow and bluegill LC50S for 48 pesticides were highly correlated. No correlations were found between fishes and rats for carbamate plus organophosphate pesticides. Correlations were obtained among all species for the combined priority pollutant plus pesticide data and for chlorinated pesticides.

• Research Organization: Univ. of Illinois, Urbana
• OSTI ID: 5776296
• Journal Information: Ecotoxicol. Environ. Saf.; (United States), Journal Name: Ecotoxicol. Environ. Saf.; (United States) Vol. 8:6; ISSN EESAD
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AQUATIC ORGANISMS
CARBAMATES
CARBONIC ACID DERIVATIVES
CARBOXYLIC ACID SALTS
COMPARATIVE EVALUATIONS
CORRELATIONS
FISHES
MAMMALS
MATHEMATICS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PESTICIDES
POLLUTION
RATS
REGRESSION ANALYSIS
RODENTS
STATISTICS
TOXICITY
VERTEBRATES
WATER POLLUTION