Genetic and physiological factors affecting repair and mutagenesis in yeast

Journal Article · Tue Jan 01 04:00:00 EST 1980 · Basic Life Sci.; (United States)

DOI:https://doi.org/10.1007/978-1-4684-3842-0_7· OSTI ID:5764748

Lemontt, J F

Current views of DNA repair and mutagenesis in the yeast Saccharomyces cerevisiae are discussed in the light of recent data and with emphasis on the isolation and characterization of genetically well-defined mutations that affect DNA metabolism in general. Various pathways of repair are described, particularly in relation to their involvement in mutagenic mechanisms. In addition to genetic control, certain physiological factors such as cell age, DNA replication, and the regulatory state of the mating-type locus are shown to also play a role in repair and mutagenesis.

• OSTI ID: 5764748
• Journal Information: Basic Life Sci.; (United States), Journal Name: Basic Life Sci.; (United States) Vol. 15; ISSN BLFSB
• Country of Publication: United States
• Language: English

Related Subjects

550400* -- Genetics
560112 -- Radiation Effects on Biochemicals-- In Microorganisms-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOCHEMICAL REACTION KINETICS
BIOLOGICAL EFFECTS
BIOLOGICAL PATHWAYS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
DNA
DNA REPLICATION
ELECTROMAGNETIC RADIATION
FUNGI
GENETIC EFFECTS
GENETIC RADIATION EFFECTS
KINETICS
METABOLISM
MICROORGANISMS
MUTAGENESIS
NUCLEIC ACID REPLICATION
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PHYSIOLOGY
PLANTS
RADIATION EFFECTS
RADIATIONS
REACTION KINETICS
RECOVERY
REPAIR
SACCHAROMYCES
SACCHAROMYCES CEREVISIAE
ULTRAVIOLET RADIATION
YEASTS