Effects of zinc, iron and copper deficiencies on cadmium in tissues of Japanese quail. [Coturnix coturnix japonica]

Journal Article · Thu Mar 01 04:00:00 EST 1984 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.1289/ehp.845457· OSTI ID:5762330

Fox, M R.S.; Tao, S H; Stone, C L; Fry, Jr, B E

Experiments with young Japanese quail were conducted to determine whether combined moderate deficiencies of zinc, iron and copper would cause greater uptake and tissue retention of cadmium than the single deficiencies. Birds were fed the experimental diets containing 62 ppb cadmium from hatching to 16 days of age. On day 9 each bird received a dose of /sup 109/CdCl/sub 2/ in its diet. On day 10, the duodenal and jejunal-ileal tissues contained large amounts of cadmium, and there were many significant effects of treatment on cadmium-109 retention in the livers and kidneys. At day 16, zinc deficiency caused increased cadmium in the liver, whereas iron and copper deficiencies each caused increased cadmium in the kidneys. Combined deficiencies had little or no greater effect than single deficiencies and in some cases the combined effect was less than that of a single deficiency. 13 references, 11 tables.

• Research Organization: Food and Drug Administration, Washington, DC
• OSTI ID: 5762330
• Journal Information: Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 54; ISSN EVHPA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIRDS
CADMIUM
COPPER
DATA
DIET
DISTRIBUTION
ELEMENTS
EXPERIMENTAL DATA
INFORMATION
IRON
ISOTOPE APPLICATIONS
METALS
NUMERICAL DATA
NUTRITIONAL DEFICIENCY
RESPONSE MODIFYING FACTORS
RETENTION
TISSUE DISTRIBUTION
TRACER TECHNIQUES
TRANSITION ELEMENTS
UPTAKE
VERTEBRATES
ZINC