Radiation absorbed doses from iron-52, iron-55, and iron-59 used to study ferrokinetics

Journal Article · Fri Apr 01 00:00:00 EST 1983 · J. Nucl. Med.; (United States)

OSTI ID:5762122

Robertson, J S; Price, R R; Budinger, T F; Fairbanks, V F; Pollycove, M

Biological data obtained principally with Fe-59 citrate are used with physical data to calculate radiation absorbed doses for ionic or weak chelate forms of Fe-52, Fe-55, and Fe-59, administered by intravenous injection. Doses are calculated for normal subjects, primary hemochromatosis (also called idiopathic or hereditary hemochromatosis), pernicious anemia in relapse, iron-deficiency anemia, and polycythemia vera. The Fe-52 doses include the dose from the Mn-52m daughter generated after injection of Fe-52. Special attention has been given to the dose to the spleen, which has a relatively high concentration of RBCs and therefore of radioiron, and which varies significantly in size in both health and disease.

• Research Organization: Diagnostic Nuclear Medicine, Mayo Clinic, Rochester, MN
• OSTI ID: 5762122
• Journal Information: J. Nucl. Med.; (United States), Vol. 24:4
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
IRON 52
UPTAKE
IRON 55
IRON 59
CALCULATION METHODS
CITRATES
ERYTHROCYTES
HEMIC DISEASES
INTRAVENOUS INJECTION
MAN
RADIATION DOSES
RADIONUCLIDE KINETICS
SPLEEN
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CARBOXYLIC ACID SALTS
DAYS LIVING RADIOISOTOPES
DISEASES
DOSES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-EVEN NUCLEI
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INJECTION
INTAKE
INTERMEDIATE MASS NUCLEI
IRON ISOTOPES
ISOTOPES
MAMMALS
MATERIALS
NUCLEI
ORGANS
PRIMATES
RADIOISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560171* - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)