Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Renal function in relation to low levels of cadmium exposure in a group of smelter workers

Journal Article · · Environ. Health Perspect.; (United States)
DOI:https://doi.org/10.1289/ehp.8454193· OSTI ID:5761766
;
Blood and urine samples were obtained from 274 smelter workers and urine samples from 48 controls. Cadmium, ..beta../sub 2/-microglobulin, and creatinine were estimated in blood and urine, and total protein in urine. Concentrations of cadmium in urine (mean 2.0 nmole/mmole creatinine) and blood (mean 21.8 nmole/L) observed in the smelter workers confirmed that this group had absorbed more cadmium than the general population, but less than most other occupationally exposed groups studied. Mean ..beta../sub 2/-microglobulin in urine was not significantly different in the smelter workers and the controls. The mean total protein in urine was 20% higher in the smelter workers, a difference which was significant. There was no consistent picture within the smelter workers of a relationship between history of cadmium exposure and the effect measures of ..beta../sub 2/-microglobulin in urine and blood, total protein in urine, creatinine clearance and relative ..beta../sub 2/-microglobulin clearance. Small but significant positive correlation coefficients were observed between cadmium in urine and ..beta../sub 2/-microglobulin in urine, total protein in urine and ..beta../sub 2/-microglobulin clearance although these may be artifactual. 14 references, 12 tables.
Research Organization:
London School of Hygiene and Tropical Medicine, England
OSTI ID:
5761766
Journal Information:
Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 54; ISSN EVHPA
Country of Publication:
United States
Language:
English

Similar Records

Cadmium concentration in the kidney cortex of occupationally exposed workers measured in vivo using X-ray fluorescence analysis
Journal Article · Tue Mar 31 23:00:00 EST 1987 · Environ. Res.; (United States) · OSTI ID:6465021
Assessment of renal function of workers exposed to inorganic lead, cadmium or mercury vapor
Journal Article · Fri Oct 31 23:00:00 EST 1980 · J. Occup. Med.; (United States) · OSTI ID:7055785
Cadmium nephropathy: monitoring for early evidence of renal dysfunction
Journal Article · Wed Jul 01 00:00:00 EDT 1981 · Arch. Environ. Health; (United States) · OSTI ID:5760231

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL ACCUMULATION
BIOLOGICAL FUNCTIONS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BLOOD
BODY
BODY FLUIDS
CADMIUM
CHEMICAL ANALYSIS
CORRELATIONS
DATA
ELEMENTS
EXPERIMENTAL DATA
FUNCTIONS
INFORMATION
KIDNEYS
MATERIALS
MEASURING METHODS
METALS
MONITORING
NUMERICAL DATA
OCCUPATIONAL EXPOSURE
ORGANS
PERSONNEL MONITORING
RADIATION MONITORING
SMELTERS
URINE
WASTES