Management of radionecrosis of the vulva and distal vagina

Journal Article · Wed May 01 04:00:00 EDT 1991 · American Journal of Obstetrics and Gynecology; (USA)

DOI:https://doi.org/10.1016/0002-9378(91)90690-S· OSTI ID:5760111

Roberts, W S; Hoffman, M S; LaPolla, J P; Ruas, E; Fiorica, J V; Cavanagh, D ^[1]

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1. Univ. of South Florida, Tampa (USA)

Twelve patients were seen between January 1983 and June 1989 with the clinical diagnosis of radionecrosis of the vulva or distal vagina. Seven patients received radiation for vulvar cancer, three for distal vaginal cancer, and two for recurrent endometrial cancer. No patient healed spontaneously and the mean delay in surgical therapy was 8.5 months. The radionecrotic site was treated with local therapy, radical local excision (with or without colostomy), or exenteration. The operative defect was closed primarily in three patients and covered with local flaps or myocutaneous flaps in seven patients. The two patients with local care still have radionecrotic ulcers. One of three patients who were closed primarily continues to have an ulcer. All other patients have healed satisfactorily except one who died after two attempts to correct the problem. Radionecrosis of the vulva and distal vagina should generally be treated surgically.

• OSTI ID: 5760111
• Journal Information: American Journal of Obstetrics and Gynecology; (USA), Journal Name: American Journal of Obstetrics and Gynecology; (USA) Vol. 164:5 Pt 1; ISSN 0002-9378; ISSN AJOGA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
FEMALE GENITALS
INJURIES
MEDICINE
NECROSIS
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SURGERY
THERAPY