Primary hyperaldosteronism: comparison of CT, adrenal venography, and venous sampling

Conference · Mon Aug 01 04:00:00 EDT 1983 · AJR, Am. J. Roentgenol.; (United States)

OSTI ID:5748212

Geisinger, M A; Zelch, M G; Bravo, E L; Risius, B F; O'Donovan, P B; Borkowski, G P

Twenty-nine patients with primary hyperaldosteronism were evaluated with computed tomography (CT), adrenal venous sampling, and adrenal venography. Twenty-three patients had aldosteronomas and six had bilateral adrenocortical hyperplasia. Sixteen (70%) of the adenomas were accurately located by CT. All nodules of 1.5 cm or larger diameter and 50% of nodules 1.0 to 1.4 cm in diameter were demonstrated. Nodules of less than 1.0 cm in diameter generally were not detected. High-resolution CT appeared more sensitive than standard CT (75% vs 58%). Adrenal venous sampling for aldosterone assay was the most sensitive of the three methods, localizing 22 (96%) of the 23 adenomas. Eighteen (78%) of the adenomas were identified by adrenal venography, although two patients with bilateral cortical hyperplasia were mistakenly diagnosed as having a small adenoma. No such false-positive studies were encountered with CT or adrenal venous sampling.

• Research Organization: Cleveland Clinic Foundation, OH
• OSTI ID: 5748212
• Conference Information: Journal Name: AJR, Am. J. Roentgenol.; (United States) Journal Volume: 141:2
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
ADRENAL GLANDS
BIOASSAY
BIOLOGICAL LOCALIZATION
BIOMEDICAL RADIOGRAPHY
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOLOGY
TOMOGRAPHY
VEINS