Standardized treatment of severe methanol poisoning with ethanol and hemodialysis

Journal Article · Thu Feb 28 23:00:00 EST 1985 · West. J. Med.; (United States)

OSTI ID:5741801

Ekins, B R; Rollins, D E; Duffy, D P; Gregory, M C

Seven patients with methanol poisoning were treated with ethanol, hemodialysis and supportive measures. The interval between ingestion and initiation of ethanol therapy varied from 3 to 67 hours and from ingestion to dialysis from 9 to 93 hours. All patients survived, but one had permanent visual impairment. A 10% ethanol solution administered intravenously is a safe and effective antidote for severe methanol poisoning. Ethanol therapy is recommended when plasma methanol concentrations are higher than 20 mg per dl, when ingested doses are greater than 30 ml and when there is evidence of acidosis or visual abnormalities in cases of suspected methanol poisoning. 13 references, 1 figure, 2 table.

• Research Organization: Univ. of Utah School of Medicine, Salt Lake City
• OSTI ID: 5741801
• Journal Information: West. J. Med.; (United States), Journal Name: West. J. Med.; (United States) Vol. 142:3; ISSN WJMDA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALCOHOLS
BIOLOGICAL MATERIALS
BLOOD
BLOOD PLASMA
BODY FLUIDS
DIALYSIS
ETHANOL
EVALUATION
HYDROXY COMPOUNDS
INGESTION
INJECTION
INTAKE
INTRAVENOUS INJECTION
MATERIALS
METHANOL
ORGANIC COMPOUNDS
PATIENTS
RECOMMENDATIONS
SEPARATION PROCESSES
THERAPY
TOXICITY