Skin exposure to I blocks thyroid uptake of 131I
Journal Article
·
· Health Phys.; (United States)
Radioisotopes of I pose an important health risk to man in nuclear accidents associated with electric power generation due to their uptake by the thyroid glands. Topical application of tincture of I or povidone-iodine to the skin of rats has been found to be as effective as oral administration of potassium iodide in blocking thyroid uptake of parenterally administered 131I. If the same effectiveness can be demonstrated in humans, this may be an attractive alternative method of mass protection from radioisotopes of I following nuclear accidents.
- OSTI ID:
- 5737305
- Journal Information:
- Health Phys.; (United States), Journal Name: Health Phys.; (United States) Vol. 5; ISSN HLTPA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560172* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ACCIDENTS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
DAYS LIVING RADIOISOTOPES
ELEMENTS
HALOGENS
INTERMEDIATE MASS NUCLEI
IODINE
IODINE 131
IODINE ISOTOPES
ISOTOPES
MAMMALS
NONMETALS
NUCLEI
ODD-EVEN NUCLEI
RADIATION PROTECTION
RADIOISOTOPES
RATS
REACTOR ACCIDENTS
RODENTS
SKIN ABSORPTION
UPTAKE
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ACCIDENTS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
DAYS LIVING RADIOISOTOPES
ELEMENTS
HALOGENS
INTERMEDIATE MASS NUCLEI
IODINE
IODINE 131
IODINE ISOTOPES
ISOTOPES
MAMMALS
NONMETALS
NUCLEI
ODD-EVEN NUCLEI
RADIATION PROTECTION
RADIOISOTOPES
RATS
REACTOR ACCIDENTS
RODENTS
SKIN ABSORPTION
UPTAKE
VERTEBRATES