Occurrence of elevated protoporphyrin levels in relation to lead burden in infants
Journal Article
·
· Environ. Res.; (United States)
Simultaneous blood lead (PbB), erythrocyte protoporphyrin (EP), and hematocrit measurements were made semiannually in 232 normal infants from 6 to 24 months of age. The PbB averaged 7 (SD = 5) and ranged from 0 to 64 ..mu..g/dl. The incidence of elevated EP, a marker for deranged heme synthesis, was unrelated to PbB at levels below 15 ..mu..g/dl but was fourfold greater among the infants with PbB above 15 ..mu..g/dl. This relationship persisted even after eliminating the 31 (4%) anemic (hematocrit < 33%) samples. The confounding effects of iron deficiency are discussed.
- Research Organization:
- Harvard Medical School, Boston, MA
- OSTI ID:
- 5729222
- Journal Information:
- Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 39:2; ISSN ENVRA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Increased erythrocyte protoporphyrins and blood lead - a pilot study of childhood growth patterns
Dose-response curves for erythrocyte protoporphyrin vs blood lead: effect of iron status
Association of erythrocyte protoporphyrin with blood lead level and iron status in the second National Health and Nutrition Examination Survey, 1976-1980
Journal Article
·
Sat Dec 31 23:00:00 EST 1988
· Journal of Toxicology and Environmental Health; (USA)
·
OSTI ID:7150230
Dose-response curves for erythrocyte protoporphyrin vs blood lead: effect of iron status
Journal Article
·
Mon Nov 30 23:00:00 EST 1987
· Environ. Res.; (United States)
·
OSTI ID:5516788
Association of erythrocyte protoporphyrin with blood lead level and iron status in the second National Health and Nutrition Examination Survey, 1976-1980
Journal Article
·
Wed Oct 01 00:00:00 EDT 1986
· Environ. Res.; (United States)
·
OSTI ID:5115338
Related Subjects
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE GROUPS
ANEMIAS
BIOLOGICAL MARKERS
BIOLOGICAL MATERIALS
BIOSYNTHESIS
BLOOD
BLOOD CHEMISTRY
BODY BURDEN
BODY FLUIDS
CARBOXYLIC ACIDS
CHILDREN
DISEASES
ELEMENTS
HEME
HEMIC DISEASES
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
INFANTS
IRON
LEAD
MATERIALS
METALS
NUTRITIONAL DEFICIENCY
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTOPORPHYRINS
SENSITIVITY
SYMPTOMS
SYNTHESIS
TRANSITION ELEMENTS
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE GROUPS
ANEMIAS
BIOLOGICAL MARKERS
BIOLOGICAL MATERIALS
BIOSYNTHESIS
BLOOD
BLOOD CHEMISTRY
BODY BURDEN
BODY FLUIDS
CARBOXYLIC ACIDS
CHILDREN
DISEASES
ELEMENTS
HEME
HEMIC DISEASES
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
INFANTS
IRON
LEAD
MATERIALS
METALS
NUTRITIONAL DEFICIENCY
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTOPORPHYRINS
SENSITIVITY
SYMPTOMS
SYNTHESIS
TRANSITION ELEMENTS