Proton and sodium 23 magnetic resonance imaging of human ocular tissues. A model study

Journal Article · Sat Oct 31 23:00:00 EST 1987 · Arch. Ophthalmol. (Chicago); (United States)

DOI:https://doi.org/10.1001/archopht.1987.01060110078036· OSTI ID:5726074

Kolodny, N H; Gragoudas, E S; D'Amico, D J; Kohler, S J; Seddon, J M; Murphy, E J; Yun, C; Albert, D M

Clinical evaluation of uveal melanomas by magnetic resonance imaging (MRI) techniques depends on developing an understanding of the appearance of these tumors in magnetic resonance (MR) images. We have determined MR characteristics of uveal melanomas by proton (1H) and sodium /sup 23/ MRI of freshly enucleated human eyes at 1.5 tesla. The MR images were obtained using two-turn proton and /sup 23/Na surface coils, designed to both transmit and receive the radiofrequency signal. Proton MRI techniques included saturation recovery and spin echo; the gradient-recalled echo technique was used for /sup 23/Na MRI. Proton and /sup 23/Na MR images provide complementary information; contrast between intraocular tumors and vitreous, lens, or subretinal hemorrhage may be varied by using MR pulse sequences that emphasize tissues based on T1, T2, proton, or sodium density values. A combination of proton and /sup 23/Na MRI provides differentiation between normal ocular structures and intraocular tumors, as well as associated complications, such as retinal detachments and subretinal hemorrhages.

• Research Organization: Massachusetts Eye and Ear Infirmary, Boston
• OSTI ID: 5726074
• Journal Information: Arch. Ophthalmol. (Chicago); (United States), Journal Name: Arch. Ophthalmol. (Chicago); (United States) Vol. 105:11; ISSN AROPA
• Country of Publication: United States
• Language: English

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550600* -- Medicine
62 RADIOLOGY AND NUCLEAR MEDICINE
ALKALI METAL ISOTOPES
ANIMALS
BARYONS
BODY
BODY AREAS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ELEMENTARY PARTICLES
EYES
FACE
FERMIONS
HADRONS
HEAD
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PROTONS
RESONANCE
SENSE ORGANS
SODIUM 23
SODIUM ISOTOPES
SPIN ECHO
STABLE ISOTOPES
SYMPTOMS
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UVEA
VERTEBRATES