Interaction between transposable phages: cip locus of prophage D3112, responsible for inhibition of integration and transposition of the related phage B39 of Pseudomonas aeruginosa

Journal Article · Tue Apr 01 00:00:00 EST 1986 · Sov. Genet. (Engl. Transl.); (United States)

OSTI ID:5724959

Gerasimov, V A; Yanenko, A S; Akhverdyan, V Z; Krylov, V N

Bacteriophage D3112 forms two types of PA01 (D3112) lysogens: those that partially, or completely, limit the growth of the related heteroimmune phage B39. DNA/DNA hybridization has shown that the lysogens of the first type always contain one copy of prophage D3112 (monolysogens), and the lysogens of the second type contain two or more copies of prophage D3112. Limitation of the growth of phage B39 on PA01 (D3112) lysogens is associated with the functioning of the locus of prophage D3112, designated as cip (control of interaction of phages). Using deletion derivatives of plasmid RP4::D3112, the cip locus was mapped at an interval of 1.3-2.45 kb of the D3112 genome. The expression of the cip locus occurs only if the D3112 genome is at the prophage state. The function of the Cip prophage of D3112 exerts an influence on early stages of development of phage B39, decreasing the efficiency of the integration and transposition processes of phage B39.

• Research Organization: All-Union Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, USSR
• OSTI ID: 5724959
• Journal Information: Sov. Genet. (Engl. Transl.); (United States), Vol. 21:10; Other Information: Translated from Genetika; 21: No. 10, 1634-1642(Oct 1985)
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
BACTERIOPHAGES
GENETIC MAPPING
GROWTH
INHIBITION
DNA
HYBRIDIZATION
TRACER TECHNIQUES
PSEUDOMONAS
GENETICS
CHROMOSOMES
GENE RECOMBINATION
GENES
LABELLED COMPOUNDS
LABELLING
NUCLEASES
PHOSPHORUS 32
PLASMIDS
TEMPERATURE EFFECTS
BACTERIA
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGY
CELL CONSTITUENTS
DAYS LIVING RADIOISOTOPES
ENZYMES
ESTERASES
HYDROLASES
ISOTOPE APPLICATIONS
ISOTOPES
LIGHT NUCLEI
MAPPING
MICROORGANISMS
NUCLEI
NUCLEIC ACIDS
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
PARASITES
PHOSPHODIESTERASES
PHOSPHORUS ISOTOPES
RADIOISOTOPES
VIRUSES
550401* - Genetics- Tracer Techniques