Sequence and timing of ventricular wall motion in patients with bundle branch block: assessment by radionuclide cineangiography

Journal Article · Mon Nov 01 04:00:00 EST 1982 · Circulation; (United States)

DOI:https://doi.org/10.1161/01.CIR.66.5.1113· OSTI ID:5723441

Rosenbush, S W; Ruggie, N; Turner, D A; Von Behren, P L; Denes, P; Fordham, E W; Groch, M W; Messer, J V

The sequence and timing were determined of inward ventricular wall motion by least-square phase analysis of radionuclide cineangiograms in 10 patients with left bundle branch block (LBBB), five patients with right bundle branch block (RBBB) and 11 patients with normal conduction. All LBBB and RBBB patients had normal coronary arteries and no segmental wall motion abnormalities. The left ventricle (LV) was divided into eight segments and the right ventricle (RV) into three; sequence and timing were scored by three observers. In normal subjects, wall motion begins in either or both ventricles and ends in the LV or both ventricles. In patients with LBBB it begins in the RV and ends in the LV; in patients with RBBB it begins in the LV and ends in the RV or both ventricles. The intraventricular wall motion is also altered in the ventricle ipsilateral to a bundle branch block. In LBBB, the mean time of onset of LV wall motion is delayed 1.9 frames (38 msec), where RV wall motion is normal. In RBBB, the onset of RV wall motion is delayed 1.3 frames (26 msec), whereas LV wall motion is not delayed. The sequence and timing of ventricular wall motion in normal conduction and bundle branch block, as represented by least-square phase analysis of radionuclide cineangiograms, conform with previous angiographic and electrophysicologic studies. Thus, this method may be useful in analyzing other conditions characterized by abnormal ventricular activation.

• OSTI ID: 5723441
• Journal Information: Circulation; (United States), Journal Name: Circulation; (United States) Vol. 66:5; ISSN CIRCA
• Country of Publication: United States
• Language: English

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