Extended x-ray absorption fine structure studies of hemoglobin

Journal Article · Sun Feb 01 04:00:00 EST 1987 · Proc. Natl. Acad. Sci. U.S.A.; (United States)

DOI:https://doi.org/10.1073/pnas.84.4.973· OSTI ID:5718015

Shulman, R G

Results of extended x-ray absorption fine structure (EXAFS) studies of the iron atom in deoxygenated hemoglobin are reviewed. It is shown that the iron-porphinato nitrogen distance has been determined to be 2.06 +/- 0.01 A by two independent investigations. Difficulties experienced in using this distance to calculate the iron's distance above the plane by triangulation are shown to be due to ignoring differences between ferrous and ferric hemes. It is concluded that the iron is 0.2 +/- 0.1/0.2 A above the plane of the nitrogens as originally shown.

• Research Organization: Yale Univ., New Haven, CT
• OSTI ID: 5718015
• Journal Information: Proc. Natl. Acad. Sci. U.S.A.; (United States), Journal Name: Proc. Natl. Acad. Sci. U.S.A.; (United States) Vol. 84:4; ISSN PNASA
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BOND LENGTHS
CARBOXYLIC ACIDS
CHEMICAL ANALYSIS
CHEMICAL BONDS
DIMENSIONS
ELEMENTS
GLOBIN
HEMOGLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
IRON
LENGTH
METALS
NONDESTRUCTIVE ANALYSIS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTEINS
STRUCTURAL CHEMICAL ANALYSIS
TRANSITION ELEMENTS
X-RAY EMISSION ANALYSIS