Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma

Journal Article · Mon May 01 00:00:00 EDT 1989 · Invest. Ophthalmol. Visual Sci.; (United States)

OSTI ID:5713545

Johnson, M A; Drum, B A; Quigley, H A; Sanchez, R M; Dunkelberger, G R

ERG and VEP responses to counterphase checkerboard stimuli were obtained from cynomolgus monkeys with monocular glaucoma induced by laser photocoagulation of the trabecular meshwork. The glaucomatous eyes showed reductions of PERG amplitude that were directly related to the histologically defined nerve damage. VEP amplitudes were also reduced in the glaucomatous eyes, but were more variable and less affected by damage than the PERG responses. An acute increase in eye pressure to 40 mm Hg in eyes without damage had no detectable effect on PERG amplitudes.

• Research Organization: Johns Hopkins Univ. School of Medicine, Baltimore, MD (USA)
• OSTI ID: 5713545
• Journal Information: Invest. Ophthalmol. Visual Sci.; (United States), Vol. 30:5
• Country of Publication: United States
• Language: English

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