Outcome of treatment by tumorectory and radiotherapy of patients with operable breast cancer

Journal Article · Thu Oct 01 04:00:00 EDT 1981 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(81)90027-4· OSTI ID:5708238

Vilcoq, J R; Calle, R; Stacey, P; Ghossein, N A

We performed a retrospective study on 314 patients treated for a localized breast cancer by tumorectomy and radiotherapy to determine the overall survival, incidence of loco-regional failure and outcome of salvage surgery. All patients were followed for at least three years. Two hundred and fourteen patients had tumors less than or equal to 3 cm and 74 had tumors less than or equal to 6 cm. The three and five years absolute survival, free of disease (NED), is 88% (276/314) and 84% (190/225). The incidence of loco-regional failures was not dependent on tumor size and did not exceed 10% for the entire group. Recurrences were common (35%) in young patients (less than or equal to30). No patient older than 50 had recurrences. Eighty-one percent of failures appeared within three years. Salvage surgery was performed on 78% (14/18) of patients with recurrences; 57% (8/14) were free of disease (NED). Local failure in this group was not necessarily associated with disseminated cancer. Tumorectomy followed by radiotherapy is an acceptable alternative to mastectomy, particularly since salvage surgery can usually be successfully performed for recurrences.

• Research Organization: Yeshiva Univ., Bronx, NY
• OSTI ID: 5708238
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 7:10; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
COMPARATIVE EVALUATIONS
DISEASES
GLANDS
MAMMARY GLANDS
MEDICINE
MORTALITY
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY