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Effect of cell-membrane composition on the growth and composition of a nonlytic enveloped mycoplasmavirus

Journal Article · · Virology; (United States)
The effect of host cell membrane composition on viral growth and membrane composition was studied using MVL2, an enveloped nonlytic mycoplasmavirus. MVL2 contains seven proteins, with molecular weights of 67,800; 63,600; 60,900; 58,000; 52,400; 20,600; and 19,100. Cells grown in a medium which altered the fatty acid composition of the cell membrane lipids gave rise to viruses with similarly altered lipids. Near the lower limit of the membrane lipid phase transition cell growth was reduced, but no effect on viral adsorption or maturation could be found.
Research Organization:
Univ. of Rochester, NY
OSTI ID:
5707835
Journal Information:
Virology; (United States), Journal Name: Virology; (United States) Vol. 106; ISSN VIRLA
Country of Publication:
United States
Language:
English