Toxicity of benzo(a)pyrene and pyrene in the mosquito Aedes aegypti, in the dark and in the presence of ultraviolet light

Journal Article · Sat Mar 01 04:00:00 EST 1986 · Chemosphere; (United States)

OSTI ID:5686605

Kagan, J; Kagan, E D

The phototoxicity of benzo(a)pyrene constitutes a much greater risk to immature forms of the mosquito Aedes aegypti than its mutagenicity of carcinogenicity. First instar larvae, fourth instar larvae, and pupae of the mosquito Aedes aegypti were treated with benzo(a)pyrene at concentrations up to 6.7 ppm, either in the dark or in the presence of long wavelength ultraviolet light (for only 30 min). The irradiations had a profound effect on the fate of first instar larvae. Their LC/sub 50/ value for 24 h survival was about 0.002 ppm. When the adult emergence was determined, the LC/sub 50/ value was about 0.0015 ppm. The development of fourth instar larvae was also modified by the photochemical treatments, with an LC/sub 50/ value for adult emergence of 0.12 ppm. The LC/sub 50/ values for the highly carcinogenic BAP are very similar to those determined for pyrene, its non-carcinogenic parent molecule. This provides one additional proof that the carcinogenicity and the phototoxicity of polycyclic aromatic hydrocarbons are not necessarily related.

• Research Organization: Univ. of Illinois, Chicago
• OSTI ID: 5686605
• Journal Information: Chemosphere; (United States), Journal Name: Chemosphere; (United States) Vol. 15:3; ISSN CMSHA
• Country of Publication: United States
• Language: English

Related Subjects

560304* -- Chemicals Metabolism & Toxicology-- Invertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AROMATICS
ARTHROPODS
BENZOPYRENE
BIOLOGICAL EFFECTS
CARCINOGENESIS
CONDENSED AROMATICS
DIPTERA
ELECTROMAGNETIC RADIATION
HYDROCARBONS
INSECTS
INVERTEBRATES
LARVAE
MOSQUITOES
NEAR ULTRAVIOLET RADIATION
ORGANIC COMPOUNDS
PATHOGENESIS
PHOTOSENSITIVITY
PYRENE
RADIATIONS
SENSITIVITY
ULTRAVIOLET RADIATION