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Subacute and chronic bone infections: Diagnosis using In-111, Ga-67 and Tc-99m MDP bone scintigraphy and radiography

Conference · · Radiology; (United States)
OSTI ID:5680421

The usefulness of indium-111 white blood cell scintigraphy in the diagnosis of subacute or chronic bone infection was examined in 21 orthopedic patients. In-111 WBC imaging was compared with gallium-67 and technetium-99m methylene diphosphonate skeletal scintigraphy and bone radiography, all studies being performed within 1 week. In-111 WBC scintigraphy showed no definite advantage over Ga-67 scintigraphy in the identification of chronic bone infection. The two tests had the same sensitivity and similar specificity. Bone radiography had a sensitivity of 60% and a specificity of 67%. A negative Tc-99m MDP bone scintigram ruled out infection, but because of low specific, final evaluation required performance of Ga-67 or In-111 WBC scintigraphy.

Research Organization:
Univ. of Miami School of Medicine, FL
OSTI ID:
5680421
Report Number(s):
CONF-851152-
Journal Information:
Radiology; (United States), Journal Name: Radiology; (United States) Vol. 155:2; ISSN RADLA
Country of Publication:
United States
Language:
English

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