Translocation of 239Pu in mice following inhalation of sized 239PuO2
Journal Article
·
· Health Phys.; (United States)
OSTI ID:5675073
This study showed that when SAS/4 mice were exposed to sized 239PuO2 only about 0.5% of the 239Pu was translocated from lung to other organs. The fraction of 239Pu translocated appeared to be independent of the particle size of the administered 239PuO2 within the range of AMADs investigated (0.8-2.2 microns). The distribution of translocated 239Pu was similar to that observed with other species in that most of the activity was associated with the lung-associated lymph nodes followed by bone and liver. The fraction of 239Pu translocated was comparable to that found in studies with rats (ICRP72) but less than that found in more extended studies with beagle dogs.
- Research Organization:
- Atomic Energy Research Establishment, Harwell, England
- OSTI ID:
- 5675073
- Journal Information:
- Health Phys.; (United States), Journal Name: Health Phys.; (United States) Vol. 4; ISSN HLTPA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Carcinogenesis From Inhaled (PuO2)-Pu-239 in Beagles: Evidence for Radiation Homeostasis at Low Doses?
The Association of Inbreeding With Lung Fibrosis Incidence in Beagle Dogs That Inhaled 238PuO2 or 239PuO2.
Retention of monodisperse or polydisperse aluminosilicate particles inhaled by dogs, rats, and mice
Journal Article
·
Wed Sep 01 00:00:00 EDT 2010
· Health Physics, 99(3):357-362
·
OSTI ID:988618
The Association of Inbreeding With Lung Fibrosis Incidence in Beagle Dogs That Inhaled 238PuO2 or 239PuO2.
Journal Article
·
Mon Sep 12 00:00:00 EDT 2011
· Radiation Research
·
OSTI ID:1033068
Retention of monodisperse or polydisperse aluminosilicate particles inhaled by dogs, rats, and mice
Journal Article
·
Fri Jul 01 00:00:00 EDT 1983
· Toxicol. Appl. Pharmacol.; (United States)
·
OSTI ID:5602682
Related Subjects
560172* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
AEROSOLS
ALPHA DECAY RADIOISOTOPES
ANIMALS
COLLOIDS
DISPERSIONS
DISTRIBUTION
EVEN-ODD NUCLEI
HEAVY NUCLEI
INHALATION
INTAKE
ISOTOPES
MAMMALS
MICE
NUCLEI
PARTICLE SIZE
PLUTONIUM 239
PLUTONIUM ISOTOPES
RADIOACTIVE AEROSOLS
RADIOISOTOPES
RODENTS
SIZE
SOLS
TISSUE DISTRIBUTION
TRANSLOCATION
VERTEBRATES
YEARS LIVING RADIOISOTOPES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
AEROSOLS
ALPHA DECAY RADIOISOTOPES
ANIMALS
COLLOIDS
DISPERSIONS
DISTRIBUTION
EVEN-ODD NUCLEI
HEAVY NUCLEI
INHALATION
INTAKE
ISOTOPES
MAMMALS
MICE
NUCLEI
PARTICLE SIZE
PLUTONIUM 239
PLUTONIUM ISOTOPES
RADIOACTIVE AEROSOLS
RADIOISOTOPES
RODENTS
SIZE
SOLS
TISSUE DISTRIBUTION
TRANSLOCATION
VERTEBRATES
YEARS LIVING RADIOISOTOPES