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Influence of inhaled cadmium on the immune response to influenza virus

Journal Article · · Archives of Environmental Health; (USA)
; ;  [1]
  1. Centre d'Etudes Pharmaceutiques (France)

Cadmium may exacerbate pulmonary infections. In a previous study, however, cadmium appeared to enhance mouse resistance to influenza pneumonia. The authors report herein on the influence of cadmium intoxication in mice on different factors of anti-influenza immunity, e.g., antibody response, local production of interferon, pulmonary cellular response, and the interaction between pulmonary alveolar macrophages and the influenza virus. Cadmium inhalation did not affect production of antibodies or interferon. The protective effect appeared to be related to an enhanced supply of phagocytic cells into the lung.

OSTI ID:
5669173
Journal Information:
Archives of Environmental Health; (USA), Journal Name: Archives of Environmental Health; (USA) Vol. 46:1; ISSN 0003-9896; ISSN AEHLA
Country of Publication:
United States
Language:
English