Positron emission tomography of the heart
Positron emission computed tomography (PCT) represents an important new tool for the noninvasive evaluation and, more importantly, quantification of myocardial performance. Most currently available techniques permit assessment of only one aspect of cardiac function, i.e., myocardial perfusion by gamma scintillation camera imaging with Thallium-201 or left ventricular function by echocardiography or radionuclide angiocardiography. With PCT it may become possible to study all three major segments of myocardial performance, i.e., regional blood flow, mechanical function and, most importantly, myocardial metabolism. Each of these segments can either be evaluated separately or in combination. This report briefly describes the principles and technological advantages of the imaging device, reviews currently available radioactive tracers and how they can be employed for the assessment of flow, function and metabolism; and, lastly, discusses possible applications of PCT for the study of cardiac physiology or its potential role in the diagnosis of cardiac disease.
- Research Organization:
- California Univ., Los Angeles (USA). Lab. of Nuclear Medicine and Radiation Biology
- DOE Contract Number:
- EY-76-C-03-0012
- OSTI ID:
- 5658002
- Report Number(s):
- UCLA-12-1232
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
BODY
CAMERAS
CARDIOVASCULAR SYSTEM
CAT SCANNING
DIAGNOSTIC TECHNIQUES
DOCUMENT TYPES
ECAT SCANNING
EVALUATION
GAMMA CAMERAS
HEART
ISOTOPE APPLICATIONS
ORGANS
PHOTON EMISSION SCANNING
PHOTON TRANSMISSION SCANNING
POSITRON CAMERAS
REVIEWS
TOMOGRAPHY
TRACER TECHNIQUES