Nuclear magnetic resonance imaging - Potential cardiac applications

Journal Article · Thu Dec 18 04:00:00 EST 1980 · Am. J. Cardiol.; (United States)

DOI:https://doi.org/10.1016/0002-9149(80)90299-4· OSTI ID:5655670

Goldman, M R; Pohost, G M; Ingwall, J S; Fossel, E T

Potential clinical applications of nuclear magnetic resonance (NMR) imaging are discussed with particular emphasis on cardiac studies. The principles of NMR spectroscopy and the reconstruction of images from NMR data obtained in a magnetic field gradient are reviewed, and the sensitive point technique of Hinshaw et al. (1977) for producing three dimensional images is introduced. Possible uses of NMR imaging in the study of intact functional biological systems are then considered, including the differentiation of ischemic tissue areas including myocardial injuries by the proton NMR imaging of water, and metabolic studies of myocardial ischemia and infarction by P-31 imaging of ATP, creatine phosphate and inorganic phosphorus. Unresolved problems in the application of NMR imaging to clinical studies are pointed out, and possible solutions which would enable the development of the technique as a powerful aid in diagnosing disease are suggested.

• Research Organization: Massachusetts General Hospital; Peter Bent Brigham Hospital; Harvard University, Boston, Mass.
• OSTI ID: 5655670
• Journal Information: Am. J. Cardiol.; (United States), Journal Name: Am. J. Cardiol.; (United States) Vol. 46; ISSN AJCDA
• Country of Publication: United States
• Language: English

Related Subjects

550600* -- Medicine
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOCHEMISTRY
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CHEMISTRY
DISEASES
HEART
IMAGE PROCESSING
IMAGES
ISCHEMIA
MAGNETIC RESONANCE
MEDICINE
NUCLEAR MAGNETIC RESONANCE
ORGANS
PH VALUE
PROCESSING
RESOLUTION
RESONANCE
SPECTROSCOPY
VASCULAR DISEASES