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U.S. Department of Energy
Office of Scientific and Technical Information

Mechanisms of interferon actions. Volume II

Book ·
OSTI ID:5654141

This 2-volume set provides an overview of the state-of-the-art in interferon research. Presenting general background material as well as the highlights of important findings, the chapters cover such topics as: the production and purification of natural and recombinant DNA-derived and interferons; the antiviral and cellular effects of interferons; interferon modulation of the immune system; the molecular mechanisms that lead to interferon induction of the antiviral state; the role of interferons in disease; and the clinical use of interferons in the treatment on human malignancies and viral infections. The Volume II discusses the following topics: Cellular Effects of Interferons. Antiproliferative Action of Interferons. Interferon-Mediated Modulation of the Immune System. Mechanisms of Action of Interferons: Evidence Studies with Recombinant DNA-Derived Subtypes and Analogs. The Interferon System and Disease. Clinical Use of Interferons in the Treatment of Viral Infections. Clinical Trials of Interferons in Human Malignancy. Index.

OSTI ID:
5654141
Country of Publication:
United States
Language:
English