Mechanisms of interferon actions. Volume I

Book · Wed Dec 31 23:00:00 EST 1986

OSTI ID:5608145

Pfeffer, L M

This 2-volume set, provides an overview of the state-of-the-art in interferon research. Presenting general background material as well as the highlights of important findings, the chapters cover such topics as: the production and purification of natural and recombinant DNA-derived and inteferons; the antiviral and cellular effects of intererons; interferon modulation of the immune system; the molecular mechanisms that lead to interferon induction of the antiviral state; the role of interferons in disease; and the clinical use of interferons in the treatment on human malignancies and viral infections. In Volume one the topics discussed are: Interferons: An Overview of Their Biolgoical and Biochemical Properties. Production and Purification of Natural Human Alpha Interferons. Production and Purification of Natural Human Beta Interferon. Production and Purification of Natural Human IFN-UPSILON. Production and Purification of Recombinant Human Interferons. Antiviral effects of Interferons in Different Virus-Host Cell Systems. Interferon Induction of the Antivrial State: Early Events. Interferon Induction of the Antiviral State: Protein Induced by Interferons and Their Possible Rules in the Antiviral Mechanisms of Interferon Action. Index.

• OSTI ID: 5608145
• Country of Publication: United States
• Language: English

Related Subjects

550200* -- Biochemistry
550400 -- Genetics
59 BASIC BIOLOGICAL SCIENCES
BIOSYNTHESIS
BIOTECHNOLOGY
CARCINOMAS
CELL KILLING
CLASSIFICATION
DISEASES
DNA
DOCUMENT TYPES
GROWTH FACTORS
HUMAN POPULATIONS
IMMUNOLOGY
IMMUNOTHERAPY
INFECTIOUS DISEASES
INTERFERON
LYMPHOKINES
MITOGENS
MODULATION
MOLECULAR BIOLOGY
NEOPLASMS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PHYSIOLOGY
POPULATIONS
PROTEINS
RECOMBINANT DNA
REVIEWS
SYNTHESIS
THERAPEUTIC USES
THERAPY
USES
VIRAL DISEASES