Computed tomography, ultrasound, and scintigraphy of the liver in patients with colon or breast carcinoma: a prospective comparison

Journal Article · Sat Oct 01 04:00:00 EDT 1983 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.149.1.6611929· OSTI ID:5653784

Alderson, O; Adams, F ^[1]; McNeil, J; Siegelman, S S; Finberg, H J; Hessel, S J; Abrams, H L

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1. Johns Hopkins Medical Inst., Baltimore, MD

A prospective evaluation of computed tomography (CT), ultrasonography (US), and Tc-99m sulfur colloid scintigraphy of the liver was performed in 189 patients who had either colon (n = 129) or breast (n = 60) carcinoma. Imaging was performed with fourth-generation CT scanners, gray-scale or phased array ultrasound scanners, and 37-tube gamma cameras. Studies were evaluated independently and receiver operting characteristic (ROC) curves were constructed. In addition, a standard 2 x 2 matrix analysis was performed. In patients who had all three examinations (n = 122), the matrix analysis showed that CT had a slightly higher sensitivity (0.93) than scintigraphy (0.86) or US (0.82); specificities were 0.88, 0.83, and 0.85, respectively. These differences were not statistically significant. However, ROC curves showed that CT had the highest true-positive ratio at every false-positive ratio, and that US had the lowest. The performance of CT did not differ sigificantly from that of scintigraphy, but was better than that of US (p < .05), especially in patients with breast carcinoma. Overall, CT provided the most accurte means for detecting liver metastases from both primary lesions.

• OSTI ID: 5653784
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 149:1; ISSN RADLA
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARCINOMAS
COLLOIDS
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
DISPERSIONS
GASTROINTESTINAL TRACT
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTESTINES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LARGE INTESTINE
LIVER
MAMMARY GLANDS
METASTASES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOCOLLOIDS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
TOMOGRAPHY
ULTRASONOGRAPHY
YEARS LIVING RADIOISOTOPES