Destruction of aromatic amines in laboratory wastes through oxidation with potassium permanganate/sulfuric acid into non-mutagenic derivatives
Nine aromatic amines, i.e., benzidine; o-tolidine; o-dianisidine; 3,3'-dichlorobenzidine; 4-aminobiphenyl; 1- and 2-naphthylamine; 4,4'-methylene bis(2-chloroaniline) and m-toluenediamine, were oxidized with potassium permanganate/sulfuric acid. Experimental conditions for complete degradation of these aromatic amines are described. The disappearance of the parent compound through oxidation was measured using HPLC coupled with UV spectrophotometry. The corresponding degradation products were found to be non-mutagenic to Salmonella typhimurium strains TA100, TA98 and TA97, both in the presence and absence of a rat liver S9 activation system. A collaborative study, involving 11 laboratories, has shown the applicability and the reproducibility of this degradation method.
- Research Organization:
- International Agency for Research on Cancer, Lyon Cedex, France
- OSTI ID:
- 5651412
- Journal Information:
- Am. Ind. Hyg. Assoc. J.; (United States), Journal Name: Am. Ind. Hyg. Assoc. J.; (United States) Vol. 46:4; ISSN AIHAA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL COMPOUNDS
AMINES
ANILINE
AROMATICS
BACTERIA
BENZIDINE
BIPHENYL
CHEMICAL REACTIONS
CHEMICAL WASTES
HYDROCARBONS
HYDROGEN COMPOUNDS
INORGANIC ACIDS
INTERLABORATORY COMPARISONS
MANGANESE COMPOUNDS
MEASURING INSTRUMENTS
METABOLIC ACTIVATION
MICROORGANISMS
MUTAGEN SCREENING
ORGANIC COMPOUNDS
OXIDATION
OXYGEN COMPOUNDS
PERMANGANATES
POTASSIUM COMPOUNDS
POTASSIUM PERMANGANATES
SALMONELLA
SALMONELLA TYPHIMURIUM
SCREENING
SPECTROMETERS
SULFURIC ACID
TRANSITION ELEMENT COMPOUNDS
ULTRAVIOLET SPECTROMETERS
WASTES