Effect of epidermal pigmentation on selective vascular effects of pulsed laser
Journal Article
·
· Lasers Surg. Med.; (United States)
The effect of epidermal pigmentation on the threshold exposure dose for inducing purpura with a tunable dye laser at 577 nm, 1.5 microseconds pulse duration, was studied in 21 human volunteers with varied genetically determined amounts of melanin. More laser energy was required to produce purpura as constitutive skin pigmentation increased. Histology showed that, in lighter skin, the laser threshold dose produced the most specific vascular injury with no disruption of surrounding structures. In more pigmented skin, damage occurred in the epidermal basal layer and very few changes were seen in blood vessels below.
- Research Organization:
- Massachusetts General Hospital, Boston
- OSTI ID:
- 5650399
- Journal Information:
- Lasers Surg. Med.; (United States), Journal Name: Lasers Surg. Med.; (United States) Vol. 4:4; ISSN LSMED
- Country of Publication:
- United States
- Language:
- English
Similar Records
Ultrastructure: effects of melanin pigment on target specificity using a pulsed dye laser (577 nm)
Effect of dye laser pulse duration on selective cutaneous vascular injury
Comparative histological studies of the tunable dye (at 577 nm) laser and argon laser: the specific vascular effects of the dye laser
Journal Article
·
Mon Jun 01 00:00:00 EDT 1987
· J. Invest. Dermatol.; (United States)
·
OSTI ID:6329634
Effect of dye laser pulse duration on selective cutaneous vascular injury
Journal Article
·
Fri Oct 31 23:00:00 EST 1986
· J. Invest. Dermatol.; (United States)
·
OSTI ID:6846364
Comparative histological studies of the tunable dye (at 577 nm) laser and argon laser: the specific vascular effects of the dye laser
Journal Article
·
Tue Sep 01 00:00:00 EDT 1981
· J. Invest. Dermatol.; (United States)
·
OSTI ID:5334981
Related Subjects
560400* -- Other Environmental Pollutant Effects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
DISEASES
DYE LASERS
ELECTROMAGNETIC RADIATION
EPIDERMIS
EPITHELIUM
HEMIC DISEASES
HYDROXY COMPOUNDS
INJURIES
LASER RADIATION
LASERS
LIQUID LASERS
MAMMALS
MAN
MAXIMUM PERMISSIBLE EXPOSURE
MELANIN
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PIGMENTS
PRIMATES
PURPURA
RADIATIONS
RESPONSE MODIFYING FACTORS
SAFETY STANDARDS
SKIN
STANDARDS
TISSUES
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
DISEASES
DYE LASERS
ELECTROMAGNETIC RADIATION
EPIDERMIS
EPITHELIUM
HEMIC DISEASES
HYDROXY COMPOUNDS
INJURIES
LASER RADIATION
LASERS
LIQUID LASERS
MAMMALS
MAN
MAXIMUM PERMISSIBLE EXPOSURE
MELANIN
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PIGMENTS
PRIMATES
PURPURA
RADIATIONS
RESPONSE MODIFYING FACTORS
SAFETY STANDARDS
SKIN
STANDARDS
TISSUES
VERTEBRATES