Studies on radiosensitive lines of Drosophila. X. Effect of 0. 8 MeV neutrons from reactor on the survival and frequency of dominant lethals in mutant line rad(2)201/sup G1/

Journal Article · Tue Apr 01 04:00:00 EST 1986 · Sov. Genet. (Engl. Transl.); (United States)

OSTI ID:5649929

Varentsova, E R; Sharygin, V I; Postnikov, L N; Efremov, O A

The frequency of dominant lethal mutations (DLM) was studied in the females of the radiosensitive mutant line rad(2)201/sup G1/ following exposure to different doses of neutrons at various stages of oogenesis. Survival of pupae after irradiation of larvae was also studied. It has been demonstrated that in respect of DLM induction, the differential sensitivity of oocytes to the action of neutrons in the control (nonmutated) line is similar to that of gamma-ray treatment. The sensitivity of oocytes at the 7th and earlier stages is higher in the mutant females than in control line. The analysis of relative biological efficiency (RBE) of the neutrons showed that they are more effective in the control line as compared to the mutant line, in respect of survival as well as frequency of DLM induction. The RBE of neutrons depended on the stage of oocyte development: the highest RBE was observed in immature sex cells of females. The possible mechanisms of higher sensitivity of mutant line rad(2)201/sup G1/ to the action of ionizing radiation are discussed.

• Research Organization: B. P. Konstantinov Institute of Nuclear Physics, Leningrad, USSR
• OSTI ID: 5649929
• Journal Information: Sov. Genet. (Engl. Transl.); (United States), Journal Name: Sov. Genet. (Engl. Transl.); (United States) Vol. 21:10; ISSN SOGEB
• Country of Publication: United States
• Language: English

Related Subjects

550400 -- Genetics
560152* -- Radiation Effects on Animals-- Animals
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ARTHROPODS
BARYONS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
COMPARATIVE EVALUATIONS
DIPTERA
DOMINANT MUTATIONS
DOSE-RESPONSE RELATIONSHIPS
DOSES
DROSOPHILA
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
ENRICHED URANIUM REACTORS
EXTERNAL IRRADIATION
FERMIONS
FERTILITY
FLIES
FRUIT FLIES
GAMMA RADIATION
GENETIC EFFECTS
GENETIC RADIATION EFFECTS
GERM CELLS
HADRONS
INSECTS
INVERTEBRATES
IONIZING RADIATIONS
IRRADIATION
IRRADIATION REACTORS
ISOTOPE PRODUCTION REACTORS
LARVAE
LETHAL MUTATIONS
MATERIALS TESTING REACTORS
MUTANTS
MUTATIONS
NEUTRON FLUENCE
NEUTRONS
NUCLEONS
OOCYTES
PUPAE
RADIATION DOSES
RADIATION EFFECTS
RADIATIONS
RADIOSENSITIVITY
REACTORS
RESEARCH AND TEST REACTORS
RESEARCH REACTORS
SURVIVAL CURVES
TANK TYPE REACTORS
THERMAL REACTORS
WATER COOLED REACTORS
WATER MODERATED REACTORS
WWR TYPE REACTORS
WWR-M-LENINGRAD REACTOR