Some effects of oral ingestion of cadmium on zinc, copper, and iron metabolism

Journal Article · Wed Jan 31 23:00:00 EST 1979 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.1289/ehp.792897· OSTI ID:5642848

Petering, H G; Choudhury, H; Stemmer, K L

Several biological effects that reflect the interaction of cadmium and zinc when cadium is ingested by rats are described. Data from several reports and investigations show that the ingestion of low levels of cadmium by rats can cause alteration of zinc metabolism in the liver, emphysema, reduced pulmonary function, depression of copper and iron metabolism in the rat fetus, growth retardation, and hemopoiesis. Because tobacco smoke contains appreciable levels of cadmium, it is recommended that research be conducted to relate the widespread incidence of emphysema throughout the U.S. to the oral ingestion of cadmium. (1 graph, 4 photos, 27 references, 5 tables)

• Research Organization: Univ of Cincinnati College of Medicine
• OSTI ID: 5642848
• Journal Information: Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 28; ISSN EVHPA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
CADMIUM COMPOUNDS
COPPER COMPOUNDS
INGESTION
INTAKE
IRON COMPOUNDS
MAMMALS
METABOLISM
RATS
RODENTS
TRANSITION ELEMENT COMPOUNDS
VERTEBRATES
ZINC COMPOUNDS