Modified acyl-ACP desaturase
Patent
·
OSTI ID:563670
Disclosed is a method for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity. 1 fig.
- Research Organization:
- Associated Universities Inc
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- AC02-76CH00016
- Assignee:
- Associated Universities, Inc., Washington, DC (United States)
- Patent Number(s):
- US 5,705,391/A/
- Application Number:
- PAN: 8-689,823
- OSTI ID:
- 563670
- Country of Publication:
- United States
- Language:
- English
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