Bone scanning in assessing viability of vascularized skeletal tissue transplants. [Rats]
Journal Article
·
· Clin. Orthop.; (United States)
OSTI ID:5607771
One hundred and eight bone scans using /sup 99m/Technetium methylene diphosphonate (MDP) were performed in rats undergoing vascularized and nonvascularized syngeneic and allogeneic transplants of the hind limb, and in control animals. A six-level system of grading the radionuclide uptake in the graft was used to evaluate healing or complications of the transplantation. Bone scanning was superior to other modalities in assessing viability of the graft. Bone scans were able to: (1) immediately confirm vascular patency, thus obviating angiography; (2) demonstrate differences in the rate of repair in syngeneic and allogeneic nonvascularized grafts; (3) sequentially assess vascularized allograft rejection; and (4) document long-term effects, such as bone atrophy due to disuse and early epiphyseal maturity.
- Research Organization:
- Mount Sinai Hospital, Toronto, Ontario, Canada
- OSTI ID:
- 5607771
- Journal Information:
- Clin. Orthop.; (United States), Journal Name: Clin. Orthop.; (United States) Vol. 160; ISSN CORPA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
560172 -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BODY
BODY AREAS
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
GRAFTS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIMBS
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
PHOSPHONATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIONUCLIDE KINETICS
RATS
RECOVERY
REPAIR
RODENTS
SCINTISCANNING
SKELETON
TECHNETIUM 99
TECHNETIUM ISOTOPES
TRANSPLANTS
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560172 -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BODY
BODY AREAS
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
GRAFTS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIMBS
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
PHOSPHONATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIONUCLIDE KINETICS
RATS
RECOVERY
REPAIR
RODENTS
SCINTISCANNING
SKELETON
TECHNETIUM 99
TECHNETIUM ISOTOPES
TRANSPLANTS
VERTEBRATES
YEARS LIVING RADIOISOTOPES