Microdosimetry of tritium

Journal Article · Wed Dec 01 04:00:00 EST 1993 · Health Physics; (United States)

DOI:https://doi.org/10.1097/00004032-199312000-00004· OSTI ID:5605100

Morstin, K; Kopec, M; Olko, P; Schmitz, T; Feinendegen, L E ^[1]

---

1. Institute of Physics and Nuclear Techniques AGH, Krakow (Poland)

Microdosimetric aspects of tritium radiotoxicity are discussed. The level of coincidence of tritium locations and of radiation-sensitive sites does not appear to be decisive for relative effectiveness of tritium exposures. The actual target structure and dimensions seem to be of more importance. Particularly efficient germ cell destruction by chronic exposures to tritiated water is unlikely to be explainable on the basis of classical principles of microdosimetry. The phenomenological approach of investigating biological response functions may be a useful alternative for the interpretation of unexpected experimental results, especially when combined with bidimensional microdosimetry. The latter allows for clustering of nanometer sites within a target of cellular dimensions. 59 refs.

• OSTI ID: 5605100
• Journal Information: Health Physics; (United States), Journal Name: Health Physics; (United States) Vol. 65:6; ISSN HLTPAO; ISSN 0017-9078
• Country of Publication: United States
• Language: English

Related Subjects

560101 -- Biomedical Sciences
Applied Studies-- Radiation Effects-- Dosimetry & Monitoring-- (1992-)
560160* -- Radionuclide Effects
Kinetics
& Toxicology
61 RADIATION PROTECTION AND DOSIMETRY
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DOSE-RESPONSE RELATIONSHIPS
DOSIMETRY
FUNCTIONS
HYDROGEN ISOTOPES
ISOTOPES
LIGHT NUCLEI
MICRODOSIMETRY
NUCLEI
ODD-EVEN NUCLEI
RADIATION EFFECTS
RADIOISOTOPES
RADIOSENSITIVITY EFFECTS
RESPONSE FUNCTIONS
TISSUES
TRITIUM
YEARS LIVING RADIOISOTOPES